Organophosphate poisoning is a neurological syndrome caused by exposure to organophosphate chemicals like those found in insecticides, herbicides, and some nerve agents. It is common in developing countries. Poisoning can occur due to occupational or accidental exposure, deliberate ingestion, or chemical warfare with nerve gases. Symptoms of acute organophosphate poisoning develop during or after exposure, within minutes to hours, depending on method of exposure. Acute Organophosphate poisoning This is the syndrome recognised by doctors and Poisons Units. The following is a list of possible symptoms of organophosphate poisoning. Organophosphate intoxication causes cholinergic symptoms early and subsequently a neuropathy with axonal degeneration producing muscle cramping and calf pain along with tingling and burning sensations in the feet. Patients exposed to high quantities of these chemicals can develop a variety of symptoms and … Blood/serum, liver, and urine can … Presentation is highly variable due to differences in dose, agent toxicity, and type of exposure. Before using any product containing organophosphate on any sick dog, consult a veterinarian. Symptoms of Organophosphate Poisoning. Nerve Agent and Organophosphate Pesticide Poisoning. Pralidoxime (2-PAM) is given after atropine to relieve neuromuscular symptoms. OPs have replaced the banned organochlorine compounds and are a major cause of animal poisoning. The present review discusses the structure of the anticholinesterase organophosphates (OPs), which are used predominantly as insecticides. The cholinergic syndrome is caused by … 2-PAM (1 to 2 g in adults; 20 to 40 mg/kg in children) is given over 15 to 30 minutes IV after exposure to an organophosphate or carbamate because, frequently, whether the poison is an organophosphate or carbamate is unknown at the time of treatment. OP poisoning can occur in a variety of situations and can be accidental or suicidal. All signs and symptoms are cholinergic in nature and affect Exposure by inhalation results in the fastest appearance of toxic symptoms, followed by the oral route and finally the dermal route. Sick dogs have a depressed immunity system and exposure to any insecticide can affect them greatly. They vary greatly in toxicity, residue levels, and excretion. Diagnostic determination of organophosphate poisoning is often accomplished by confirming reduced acetylcholinesterase (AChE) activity in blood or brain. 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